The principle of operation of organoids is similar to the functioning of an ordinary computer chip. They receive and send signals through neurons, which act like electric circuits. However, living neurons consume 1 million times less energy compared to digital processors.
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The experts cultured the stem cells for a month until they formed neuron-like elements. Mini-brain was formed from 10 thousand living neurons with a diameter of approximately 0.5 mm.
Organoids were “trained” with the help of dopamine. After the correct fulfilment of the task, they received as a reward a stream of chemical substance. In addition, the mini-brain was surrounded by 8 electrodes and current was passed through them to influence the neuron. The electrodes carried out stimulation as well as recording the information being processed.